Hexylene Glycol

Cas Number


99210-90-9 (R)

99210-91-0 (S)

Other Names

Hexylene glycol





The formula



2-Methyl-2,4-pentanediol (MPD) is an organic compound with the formula (CH3)2C(OH)CH2CH(OH)CH3. This colourless liquid is a chiral diol. It is produced industrially from diacetone alcohol by hydrogenation. Total European and USA production was 15000 tonnes in 2000. 2-Methyl-2,4-pentanediol exists as two enantiomers, (4R)-(-) and (4S)-(+). In the Protein Data Bank, the 3-letter code "MPD" refers to the (S)-(-) enantiomer, while "MRD" is used to refer to the (R)-(+) version. Commercial products labeled "MPD" are usually the racemate, also sold as and referred to as "hexylene glycol".

Physical and Chemical Properties
Physical state and Appearance: Liquid.
Odor: Sweetish
Molecular Weight: 118.18 g/mole
Color: Colorless
Boiling Point: 197 (386.6) - 198° C
Melting Point: -50 - (-58)
Specific Gravity: 0.9254 @ 17 C; 0.9234 @ 20 C (Water = 1)
Vapor Pressure: 0.05 mm of Hg (@ 20)
Vapor Density: 4.1 (Air = 1)
Odor Threshold: 50 ppm
Dispersion Properties: See solubility in water, diethyl ether
Solubility: Easily soluble in cold water. Soluble in diethyl ether. Soluble in alcohol, lower aliphatic hydrocarbons. Soluble in a variety of organic solvents. Miscible with fatty acids
Specific Gravity 20/20 °C: 0.9232
Distillation Range at 760 mm Hg (IP) °C: 196.4
Distillation Range at 760 mm Hg (DP) °C: 198.2
Purity, % w/w: 99.62
Acidity as acetic Acid, % w/w: 0.001
Water, % w/w: 0.018

2-Methyl-2,4-pentanediol (MPD) is used in aquious emultions (pvc / acrylics), paint & varnishes, hydraulic fluids, oil & emultions to textile & leather ind, anti caking for chemicals and deravitives industries, pesticides, perfumes & cosmetics and pharma intermediateries.