Dimethyl Sulfoxide

Cas Number


Other Names


Methyl sulfoxide

The formula



Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high melting point. DMSO has the unusual property that many individuals perceive a garlic-like taste in the mouth after contact with the skin.

Physical and Chemical Properties
Physical state and appearance Liquid
Odor Amine like. (Slight.)
Molecular Weight 73.09 g/mole
Color Colorless to light yellow
Boiling Point 153°C (307.4°F)
Flash point 58 °
Melting Point -61°C (-77.8°F)
Specific Gravity 0.949 (Water = 1)
Vapor Pressure 0.3 kPa (@ 20°C)
Vapor Density 2.51 (Air = 1)
Odor Threshold 100 ppm
Solubility Easily soluble in cold water, hot water. Soluble in diethyl ether, acetone. Miscible organic solvents. Soluble in benzene, and chloroform.
Content by dmso % ≥ 99.80
Freezing point °c ≥ 18.10
Acid value mgkoh/g ≤ 0.03
Water % ≤ 0.10
Transmittance (400n m) % ≥ 96.00
Pefractive index 20 °c 1.4780-1.4790
Total impurities % ≤ 0.1
pt-co chrominance ≤ 10

1. Pharmaceutical grade DMSO demonstrates a range of pharmacological activity including analgesia and anti-inflammation. Due to its ability to penetrate biological membranes, it is used as a vehicle for the transdermal delivery of active pharmaceuticals. It is also used to protect tissue during cryopreservation

2. Its use as a solvent, both in organic synthesis and industrial applications (polymer chemistry, pharmaceuticals and agrochemicals)

3. DMSO also makes a very good paint stripper as it is able to remove many paints from both wood and metal in a small amount of time